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Job Description Summary

A Research Specialist IV (RS4) laboratory manager is needed to support glycomics and extracellular matrix research and analytical assay development for three research laboratories housed within the MUSC Proteomics Center. This Center is supported by federal and foundation research grants to the individual investigators, Professors Drake, Mehta and Angel, as well as the NIDDK Digestive Disease Research Center Core grant. The RS4 will be responsible for managing multiple research budgets, oversee ordering of supplies and reagents, direct routine maintenance of multiple mass spectrometers and be the point of contact for the instrument manufacturer. The RS4 will also be the point of contact for personnel within the facility, and will ensure all laboratory staff follow and adhere to safety and all applicable health policies and regulations.
It is expected that the candidate will have a Bachelor of Science degree in chemistry, biochemistry or related field and have at least 5 years relevant experience in a mass spectrometry research laboratory. This should include at least one year of experience in supervising and/or lab management of a mass spectrometry laboratory. Research experience is expected in using MALDI mass spectrometers for tissue and biofluid imaging applications, as well as high pressure liquid chromatography-linked electrospray ionization mass spectrometers for proteomic analysis.

Entity

Medical University of South Carolina (MUSC - Univ)

Worker Type

Employee

Worker Sub-Type​

Research Grant

Cost Center

CC001032 COM PHARM Administration CC

Pay Rate Type

Salary

Pay Grade

University-07

Pay Range

57,334.00 - 81,707.00 - 106,080.000

Scheduled Weekly Hours

40

Work Shift

Job Description

Job Duties Performed:

30% Performs MALDI mass spectrometry imaging experiments on tissues and biofluids as part of joint research projects within the three laboratory groups. Performs routine diagnostic and maintenance of three MALDI mass spectrometers.

30% Performs tandem mass spectrometry protein and glycoprotein experiments on tissues and biofluids as part of joint research projects within the three laboratory groups. Performs routine diagnostic and maintenance of two HPLC systems and one timsTOF mass spectrometer.

15% Performs training of new personnel to the laboratories for use of all mass spectrometers, and assist current laboratory personnel in continued training and new method development.

10% Maintains additional laboratory equipment by performing checklist systems suitability and required maintenance. Serve as the point of contact for instrument manufacturers and liaison to department administrative staff.

15% Keeping the lab safe, clean and compliant by maintaining a neat work space, wearing appropriate personal protective equipment, and helping with labeling and inspection of laboratory items and solutions

General Nature of Work:

Directs large, complex research projects in a clinical or research setting, ensuring all laboratory staff follow and adhere to safety and all applicable health policies and regulations.

Guidelines for Class Use/Distinguishing Characteristics:

This is a supervisory class with responsibility for a large laboratory performing a high volume of tests, procedures or examinations.

Examples of Work:

Plans and directs new and innovative research projects and concepts, in collaboration with the principal investigators. Oversees and reviews the activities of employees, graduate assistants and others engaged in research or related activities, ensuring all lab employees follow industry standards and safety regulations for handling and disposing of test samples. Monitors all lab personnel to ensure adherence to safety and health policies and regulations, as well as federal and state mandates and accepted scientific practices. Performs highly specialized and complex research examinations, procedures and tests; may conduct specialized research. Develops, oversees or conducts technical training. Operates, maintains and repairs complex scientific equipment. Plans and organizes research and evaluation of scientific literature; composes and reviews articles for publication in scientific journals. Uses manual and computer techniques to analyze research data. Prepares periodic and special narrative and statistical reports to advise principal investigators and others on research techniques and procedures. Oversees or performs examination and testing of human subjects for research purposes. Functions as principal investigator for less complex research projects. Develops and recommends changes in technical and administrative policies, procedures and protocols. Develops data and recommendations for budget proposals. Provides technical consultative services. Handles confidential documents and ensures that all information and data collected in the research laboratory is kept safe, often requiring use of special software and computers. Trains lab technicians and assistants on the correct use of lab equipment, in addition to mentoring and disciplining lab staff.

MUSC Minimum Qualifications:

Bachelor of Science degree in medical technology, microbiology, biochemistry or a closely related field and four years’ relevant experience in a clinical or research laboratory environment; relevant experience includes minimum of one year of experience supervising or managing a research laboratory.

Additional Knowledge, Skill and Abilities:

Knowledge of the principles, laboratory applications and information sources for the natural sciences. Knowledge of laboratory methods, equipment, facilities and materials. Knowledge of laws and licensure programs applicable to laboratory activities. Skill in the operation, maintenance and repair of laboratory equipment. Ability to perform complex mathematical calculations. Ability to perform laboratory tests and examinations, research, analysis and consultative activities independently. Ability to develop, evaluate and implement research methodologies and laboratory procedures. Ability to plan, organize and evaluate the activities of others. Ability to supervise the work of other technical and nontechnical personnel. Ability to follow complex instructions. Ability to communicate effectively. Ability to perceive colors normally and to make olfactory distinctions. Must possess excellent interpersonal communication skills and be able to lead and direct others. Demonstrates understanding and skill in information management, performance improvement principles, mission, vision and values and age specific and medical emergency response, as applicable.

Additional Knowledge, Skill and Ability Preferred: A bachelor's degree in chemistry, biochemistry or related analytical science and 5 years relevant experience in a mass spectrometry laboratory. The ideal candidate will have at least one year of experience in supervising and/or lab management of a mass spectrometry laboratory. Research experience is expected in using MALDI mass spectrometers for tissue and biofluid imaging applications, as well as high pressure liquid chromatography-linked electrospray ionization mass spectrometers for proteomic analysis.

Additional Job Description

Minimum Requirements: Bachelor of Science degree in medical technology, microbiology, biochemistry or a closely related field and four years’ relevant experience in a clinical or research laboratory environment; relevant experience includes minimum of one year of experience supervising or managing a research laboratory.” Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Frequent) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb, using step stool. (Infrequent) Ability to work in temperature extremes (32° F to 100° F) when required due to assignments in cold rooms and/or foreign countries. (Infrequent) Ability to work in confined/cramped spaces. (Continuous) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Frequent) Ability to fully use both legs. (Frequent) Ability to reach in all directions, stretch, bend, while moving items/materials from both sitting and standing positions. (Frequent) Ability to maintain good olfactory sensory function/distinction. (Continuous) Ability to lift materials up to 20 lbs., unassisted. (Infrequent) Ability to lift and carry 4 liter waste material bottles a distance of 30 feet, unassisted. (Frequent) Ability to lift and carry 25-30 lbs. jugs of liquid a distance of 100 feet, unassisted. (Infrequent) Ability to lift file boxes, from floor level to counter tops, unassisted. (Frequent) Ability to push/ Ability to lift 40 lbs. centrifuge rotors from floor level to height of 40 inches, then down 20 inches into centrifuge drum, unassisted. (Infrequent) Ability to lift 25 lbs. boxes, from floor level to maximum height of 72 inches, unassisted. (Infrequent) Ability to push/pull file boxes from one location to another at floor level. (Frequent) Ability to maneuver heavy equipment on bench tops, 50 lbs. or greater, unassisted. (Frequent) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to maintain 20/40 vision, corrected, in one eye or with both eyes. (Continuous) Ability to match or discriminate between colors, normally. (Continuous) Ability to hear and recognize various alarms emitting from work area systems. (Continuous) Ability to hear and/or understand conversations. (Continuous) Ability to work in a darkroom for processing film, etc. (Continuous) Ability to be qualified physically for respirator use, initially and annually. (Continuous) Additional New Requirements: Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required.

If you like working with energetic enthusiastic individuals, you will enjoy your career with us!

The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.

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